53 Ab-8 Mouse Monoclonal Antibody, Deliver Accurate, Reproducible Results With The P53 Ab-8, Mouse Monoclonal Antibody, Each

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53 Is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, sv40 t antigen and human papilloma virus e6 protein p53 senses dna damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host species: mouseclone: do-7 bp53-12isotype: igg2b igg2aspecies reactivity: human. Others not known.Epitope: aa 37-45 and aa 20-25immunogen: recombinant human p53 proteinmolecular weight: 53kdapositive control: mda-231, skbr-3 cells or colon cacellular localization: nuclear recommended for:immunohistochemistry (formalin/paraffin)western blottingimmunoprecipitation (native and denatured)