Upa Inhibitor Ii, Uk122, Each

Details:

A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activatorupa inhibitor ii, uk122 acts as a potent, selective and active-site targeting urokinase-type plasminogen activator (upa) inhibitor. However, its activity against trypsin, thrombin, tpa, and plasmin is greatly reduced. It is also effectively inhibits the migration (80% inhibition) and invasion (68% inhibition) of upa-expressing cfpac-1 pancreatic cells, without affecting its proliferation. A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator