Aph1a Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Aph1a, Each

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Aph1 is a multipass transmembrane protein that interacts with presenilin (see psen1; mim 104311) and nicastrin (aph2; mim 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (app; mim 104760) and notch (mim 190198).[Supplied by omim