Apoe Goat Anti-Human, Polyclonal Antibody, Abnova, Goat Polyclonal Antibody Raised Against Native Apoe, Each

Details:

Chylomicron remnants and very low density lipoprotein (vldl) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein e, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. Apoe is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The apoe gene is mapped to chromosome 19 in a cluster with apoc1 and apoc2. Defects in apolipoprotein e result in familial dysbetalipoproteinemia, or type iii hyperlipoproteinemia (hlp iii), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and vldl remnants. [Provided by refseq