Atf6b Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Atf6b, Each

Details:

The protein encoded by this gene is a transcription factor in the unfolded protein response (upr) pathway during er stress. Either as a homodimer or as a heterodimer with atf6-alpha, the encoded protein binds to the er stress response element, interacting with nuclear transcription factor y to activate upr target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under er stress, the n-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [Provided by refseq