Calnexin Mouse, Unlabeled, Clone: 37, Bd, Mouse Monoclonal Antibody, Each

Details:

Calnexin is a 90kda integral membrane protein located primarily in the er. It contains a long n-terminal calcium-binding domain that extends into the lumen of the er and a short, acidic cytosolic domain. Calnexin associates with several cell surface proteins as they pass through the er. Since it also forms complexes with other resident er proteins involved in the ca2+-dependent retention of proteins, calnexin may act as a chaperone. The amino acid sequence of calnexin is highly conserved among species and is similar in sequence to calreticulin, another ca2+-binding protein found in the er. Neither calnexin nor calreticulin contain the calcium-binding motif, known as the “e-f hand” found in the calmodulin family of proteins.Host species: mouseclone: 37isotype: igg1species reactivity [for features main]: humanimmunogen: human calnein aa. 116-301Immunofluorescence, immunoprecipitatio