Cd102 Rat Anti-Mouse, Na/Le, Unlabeled, Clone: 3c4 (Mic2/4), Bd, Rat Monoclonal Antibody, Each

Details:

The 3c4 (mic2/4) antibody reacts with the mouse icam-2 (cd102) cell surface glycoprotein, a ligand for lfa-1. Cd102 is constitutively expressed on endothelial cells, t and b lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. Cd102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial cd102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3c4 (mic2/4) antibody blocks interactions between icam-2 and lfa-1.