Cd107a Rat Anti-Mouse, Fitc, Clone: 1d4b, Bd, Rat Monoclonal Antibody, Each

Details:

The 1d4b antibody recognizes cd107a (lysosome-associated membrane protein 1, lamp-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse cd107a consists of a 40kda core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140kda. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human lamp-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.Host species: ratclone: 1d4bisotype: igg2a κspecies reactivity: mouseimmunogen: plasma membrane fraction of mouse embryo nih 3t3 cell lineintracellular staining