Cd11a Mouse Anti-Human, Unlabeled, Clone: Hi111, Bd, Mouse Monoclonal Antibody, Each

Details:

Reacts with the 180kda integrin α chain which associates with cd18 (integrin β2) to form the heterodimer glycoprotein cd11a/cd18. This is known as the lymphocyte function associated antigen-1 (lfa-1), which is on all leukocytes; and is an adhesion molecule involved in lymphocyte and granulocyte functions. Lfa-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (icam-1), cd54. Other ligands are icam-2 (cd102) and icam-3 (cd50). This antibody is routinely tested by flow cytometric analysis. Other applications were tested at bd biosciences pharmingen during antibody development only or reported in the literature.