Cd11c Mouse Anti-Human, Brilliant Violet 421, Clone: 3.9, Bd, Mouse Monoclonal Antibody, Each

Details:

The 3.9 Monoclonal antibody specifically binds to cd11c, which is also known as integrin alpha x ( α x integrin/itgax), or p150,95 integrin alpha chain. Cd11c is a ∽150 kda type i transmembrane glycoprotein. It is expressed on monocytes, macrophages, granulocytes, nk cells, dendritic cells, and subsets of b and t cells. It associates with cd18 (integrin beta 2/ β 2 integrin) to form the cd11c/cd18 complex, which is also known as p150,95 integrin, or the type 4 complement receptor (cr4). Cd11c/cd18 binds fibrinogen and reportedly serves as a receptor for ic3b and icam-1/cd54. Cd11c/cd18 functions as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium. The 3.9 Monoclonal antibody crossreacts with rhesus macaque leucocytes.