Cd14 Mouse Anti-Human, Brilliant Violet 421, Clone: M5e2, Bd, Mouse Monoclonal Antibody, Each

Details:

The m5e2 monoclonal antibody specifically binds to cd14, a 53–55 kda glycosylphosphatidylinositol (gpi)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-cd14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some langerhans cells. Cd14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (lps) and serum lps-binding protein, lpb. The antibody was conjugated to bd horizon bv421 which is part of the bd horizon brilliant™ violet family of dyes. With an ex max of 407-nm and em max at 421-nm, bd horizon bv421 can be excited by the violet laser and detected in the standard pacific blue™ filter set (eg, 450/50-nm filter). Bd horizon bv421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to pacific blue conjugates.