Cd14 Mouse Anti-Human, Brilliant Violet 605, Clone: M5e2, Bd, Mouse Monoclonal Antibody, Each

Details:

The m5e2 monoclonal antibody specifically binds to cd14, a 53–55 kda glycosylphosphatidylinositol (gpi)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-cd14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some langerhans cells. Cd14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (lps) and serum lps-binding protein, lpb. This antibody is conjugated to bd horizon bv605 which is part of the bd horizon brilliant™ violet family of dyes. With an ex max of 407-nm and em max of 602-nm, bd horizon bv605 can be excited by a violet laser and detected with a standard 610/20-nm filter set. Bd horizon bv605 is a tandem fluorochrome of bd horizon bv421 and an acceptor dye with an em max at 605-nm. Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the pe and bd horizon pe-cf594 detectors off the green or yellow-green lasers. Bd horizon bv605 conjugates are very bright, often exhibiting brightness equivalent to pe conjugates and can be used as a third color off of the violet laser.