Cd16 Mouse Anti-Human, Brilliant Violet 421, Clone: 3g8, Bd, Mouse Monoclonal Antibody, Each

Details:

The 3g8 monoclonal antibody specifically binds to the 50-65 kda transmembrane form of the igg fc receptor (fcγriii), a human nk-cell-associated antigen. Cd16 is expressed on nk cells as well as macrophages and granulocytes. Reports indicate that cd16 plays a role in signal transduction and nk cell activation. The 3g8 antibody blocks the binding of soluble immune complexes to granulocytes.The antibody was conjugated to bd horizon™ bv421 which is part of the bd horizon™ brilliant violet™ family of dyes. With an ex max of 407nm and em max at 421nm, bd horizon™ bv421 can be excited by the violet laser and detected in the standard pacific blue™ filter set (eg, 450/50nm filter). Bd horizon™ bv421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to pacific blue™ conjugates.Host species: mouseclone: 3g8isotype: igg1, κspecies reactivity: huimmunogen: human polymorphonuclear leukocytesflow cytometry