Cd184 Mouse Anti-Human, Apc, Clone: 12g5, Bd, Mouse Monoclonal Antibody, Each

Details:

Reacts with fusin (cxcr4), a seven-transmembrane domain, g-protein-linked glycoprotein. Fusin is expressed on a wide variety of cd4+ and cd4- cells including those from spleen, brain and lung. It has been shown to function as a cofactor for infection with t-cell tropic strains of hiv-1 and also as a receptor for cd4-independent infection. 12G5 antibody has been reported to block cd4-independent infection by hiv-2 and cd4-dependent infection by some t-cell tropic isolates of hiv-1.Host species: mouseclone: 12g5isotype: igg2a κspecies reactivity: humanflow cytometry