Cd23 Mouse Anti-Human, Unlabeled, Clone: M-L233, Bd, Mouse Monoclonal Antibody, Each

Details:

The m-l233 antibody reacts with the low affinity receptor for human ige, fcεrii/cd23. Cd23 is a type ii membrane protein which can be expressed by b cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. Cd23 can mediate ige-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble cd23 (scd23) can be released by cd23+ cells as a result of proteolytic cleavage of membrane cd23. Larger fragments of scd23 (e.G., 37-25Kda) retain their ige-binding capacity whereas smaller fragments (i.E., ≪12kda) do not. Soluble cd23 may have immunoregulatory effects on the growth and differentiation of b cells and other cell types.Host species: mouseclone: m-l233isotype: igg1 κspecies reactivity: humanimmunohistochemistry, immunohistochemistry (frozen)