Cd25 Mouse Anti-Human, Brilliant Violet 786, Clone: M-A251, Bd, Mouse Monoclonal Antibody, Each

Details:

The m-a251 monoclonal antibody specifically binds to the 55 kda type i transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (il-2r α ). Cd25 is expressed on regulatory t cells and on activated lymphocytes (t and b) and monocytes. It associates with the il-2r β /cd122 and the il-2r γ/cd132 receptor chains to form the high-affinity il-2r complex. Cd25 expression on t and b lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble cd25/il-2r α is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.