Cd27 Mouse Anti-Human, Brilliant Violet 421, Clone: M-T271, Bd, Mouse Monoclonal Antibody, Each

Details:

The m-t271 monoclonal antibody specifically binds to cd27. Cd27 presents as a type i transmembrane, disulphide-linked 110 kda homodimer comprised of two polypeptide chains. The cd27 molecule is a lymphocyte-specific member of the tnf/ngf-r family, and is expressed on a subset of human thymocytes and on the majority of mature t lymphocytes, activated b cells and nk cells. Cd27 is highly induced on t cells after tcr stimulation. Cd27 binds to cd70 (also known as, cd27 ligand or cd27l) and may be involved in cellular interaction of t and b lymphocytes. The antibody was conjugated to brilliant violet 421 and has been developed in collaboration with sirigen. With an ex max of 407-nm and em max at 421-nm, brilliant violet 421 can be excited by the violet laser and detected in the standard pacific blue filter set (eg, 450/50-nm filter). Brilliant violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to pacific blue conjugates.Host species: mouseclone: m-t271isotype: igg1, κspecies reactivity: humanflow cytometry