Cd3 Mouse Anti-Human, Pe, Clone: Ucht1, Bd, Mouse Monoclonal Antibody, Each

Details:

The ucht1 monoclonal antibody specifically binds to the human cd3ε-chain, a 20-kda subunit of the cd3/t cell antigen receptor complex. Cd3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the hlda workshop show that this antibody is mitogenic for cd3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-cd28 antibody. Cd3 plays a central role in signal transduction during antigen recognition. The ucht1 antibody stains both surface and intracellular cd3ε unlike the other cd3 clone, hit3a, that stains only extracellular cd3ε.