Cd3e Hamster Anti-Mouse, V450, Clone: 500a2, Bd, Hamster Monoclonal Antibody, Each

Details:

This antibody has been reported to react with the 25-kda ε chain of the t-cell receptor-associated cd3 complex expressed on thymocytes, mature t lymphocytes, and nk-t cells on many mouse stains. Plate-bound and soluble hamster anti-mouse cd3e (clone 500a2) antibody has been reported to activate unprimed t cells in vitro. Activation of a mouse t-cell clone by soluble hamster anti-mouse cd3e (clone 500a2) can be blocked by fab fragments of anti-cd4 antibody gk1.5, Suggesting that the hamster anti-mouse cd3e (clone 500a2) antibody may bind an epitope of cd3e close to a site at which cd4 associates with the t-cell receptor. This hamster mab to a mouse leukocyte antigen has been reported not to cross-react with rat leukocytes. The antibody is conjugated to bd horizon™ v450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from bd biosciences. It is excited by the 450 nm. Conjugates with bd horizon™ v450 can be used in place of pacific blue™ conjugates.