Cd49a Hamster Anti-Rat/Mouse, Percp-Cy5.5, Clone: Ha31/8, Bd, Hamster Monoclonal Antibody, Each

Details:

The ha31/8 monoclonal antibody specifically binds to the 180-kda integrin α 1 chain (cd49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin β 1 subunit (cd29) to form the α 1β 1 (complex known as vla-1). Vla-1 has been reported to be expressed on activated t cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The ha31/8 monoclonal antibody is specific for both rat and mouse cd49a. It has been reported that ha31/8 antibody can block vla-1-mediated binding of rat cells to collagen.