Cd62l Mouse Anti-Human, Pe-Cf594, Clone: Dreg 56, Bd, Mouse Monoclonal Antibody, Each

Details:

Thedreg-56 monoclonal antibody specifically binds to cd62l. Cd62l is a 76-95 kda glycoprotein that is also referred to as l-selectin or lecam-1. Cd62l is expressed on neutrophils, monocytes, t- and b-lymphocyte subsets and nk cells. The dreg-56 antibody recognizes the same antigen as lam-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (hev) in frozen sections of peripheral, but not mucosal lymphoid tissue. It thus defines l-selectin as a human lymphocyte homing receptor for peripheral lymph node hev. This antibody is conjugated to bd horizon™ pe-cf594, which has been developed exclusively by bd biosciences as a better alternative to pe-texas red. Pe-cf594 excites and emits at similar wavelengths to pe-texas red yet exhibits improved brightness and spectral characteristics. Due to pe having maximal absorption peaks at 496nm and 564nm, pe-cf594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as pe-texas red (eg 610/20-nm filter).