Cd64 Mouse Anti-Human, Pe-Cf594, Clone: 10.1, Bd, Mouse Monoclonal Antibody, Each

Details:

The 10.1 Monoclonal antibody specifically binds to cd64, a 72 kda type i transmembrane glycoprotein that is a high affinity receptor for human igg (fcγri), especially the igg1 and igg3 subclasses. Cd64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. Cd64 associates with a signaling fcrγhomodimer to form the functional high affinity fcγri complex. Cd64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.