Cd83 Mouse Anti-Human, Brilliant Violet 786, Clone: Hb15e, Bd, Mouse Monoclonal Antibody, Each

Details:

The hb15e monoclonal antibody specifically binds to a 45 kda type 1 transmembrane glycoprotein member of the ig superfamily. Cd83 is composed of a single v-type ig extracellular domain with a c-terminal cytoplasmic tail. Cell surface cd83 is expressed mainly by follicular dendritic cells, circulating dendritic cells, interdigitating dendritic cells in lymphoid tissues, in vitro-generated dendritic cells and thymic dendritic cells. However, its expression is not restricted to dendritic cells. Cd83 is also expressed on some germinal center b cells and some lymphoblastoid cell lines. Although its function is not known, it may play a role in cell-cell interaction during antigen presentation. The antibody was conjugated to bd horizon bv786 which is part of the bd horizon brilliant™ violet family of dyes. This dye is a tandem fluorochrome of bd horizon bv421 with an ex max of 405-nm and an acceptor dye with an em max at 786-nm. Bd horizon bv786 can be excited by the violet laser and detected in a filter used to detect cy™7-like dyes (eg, 780/60-nm filter).