Cd86 Mouse Anti-Human, Brilliant Violet 510, Clone: 2331(Fun-1), Bd, Mouse Monoclonal Antibody, Each

Details:

The 2331 (fun-1) monoclonal antibody specifically recognizes a 75 kda transmembrane cell surface protein, cd86 (b70/b7-2), expressed primarily on monocytes, dendritic cells and activated b cells. Competitive binding assays demonstrate that, while both 2331 (fun-1) and it2.2 (Anti-cd86, cat. No. 555663) Antibodies specifically recognize the same molecule, they react with different epitopes. Cd86 is the second ligand for cd28 and ctla-4 and may play an important role in co-stimulation of t cells in primary immune response. The 2331 (fun-1) antibody blocks the costimulatory activity of cd86 when tested in functional studies. The antibody was conjugated to bd horizon™ bv510 which is part of the bd horizon™ brilliant violet™ family of dyes. With an ex max of 405-nm and em max at 510-nm, bd horizon™ bv510 can be excited by the violet laser and detected in the bd horizon™ v500 (525/50-nm) filter set. Bd horizon™ bv510 conjugates are useful for the detection of dim markers off the violet laser.