Cd86 Mouse Anti-Human, Fitc, Clone: 2331 (Fun-1), Bd, Mouse Monoclonal Antibody, Each

Details:

2331 (Fun-1) recognizes a 75kda cell surface protein, cd86 (b70/b7-2), expressed primarily on monocytes and activated b cells. Competitive binding assays demonstrate that, while both 2331 (fun-1) and it2.2 (Anti-cd86) recognize the same molecule, they react with different epitopes. Cd86 is the second ligand for cd28 and ctla-4 and may play an important role in co-stimulation of t cells in primary immune response. 2331 (Fun-1) blocks costimulation activity of cd86 in functional studies. Other applications were tested at bd biosciences pharmingen during antibody development only or reported in the literature.