Dph1, Rabbit, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Dph1, Each

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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (eef2; mim 130610). This modification is conserved from archaebacteria to humans and serves as the target for adp-ribosylation and inactivation of eef2 by diphtheria toxin (dt) and pseudomonas exotoxin a. Dph1 is 1 of several enzymes involved in synthesis of diphthamide in eef2 (liu et al., 2004 [Pubmed 15485916]).[Supplied by omim