Egf Receptor Mouse, Unlabeled, Clone: 13, Bd, Mouse Monoclonal Antibody, Each

Details:

Epidermal growth factor (egf) elicits a variety of cellular responses that are initiated by egf receptor (egf-r) binding and activation of intrinsic tyrosine kinase activity. Following ligand binding, egf receptor is autophosphorylated and, in turn, phosphorylates several other endogenous proteins including phospholipase c γ . These events initiate a number of intracellular responses that include increased levels of intracellular ca2+ and transient expression of the nuclear oncogene products c-myc and c-fos.