Eif4g2, Rabbit, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Eif4g2, Each

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Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4f (eif4f), which is a cap binding protein complex that consists of three subunits: eif4a, eif4e and eif4g. The protein encoded by this gene shares similarity with the c-terminal region of eif4g that contains the binding sites for eif4a and eif3; eif4g, in addition, contains a binding site for eif4e at the n-terminus. Unlike eif4g, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mrna initiates exclusively at a non-aug (gug) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [Provided by refseq