Emd 386088 Hydrochloride, Potent 5-Ht6 Agonist, Each

Details:

Emd 386088 hydrochloride is a potent 5-ht6 receptor agonist (ec50 = 1.0 Nm) that displays selectivity over other 5-ht receptors (ic50 values are 7.4, 110, 180, 240, 450, 620, 660 And 3000 nm for 5-ht6, 5-ht1d, 5-ht1b, 5-ht2a, 5-ht2c, 5-ht4, 5-ht1a and 5-ht7 receptors respectively). Shows moderate affinity at 5-ht3 receptors (ic50 = 34 nm).