Complement C9, Human, Protein, Each

Details

Native, human c9 complement component. Single-chain glycoprotein present in normal human serum at 60μg/ml. On activation of complement via either the classical or alternative pathway, formation of the c5b fragment initiates assembly of the c5b-9 complement membrane attack complex (mac) on target surfaces. Full lytic activity of mac occurs only after binding of three to six c9 molecules to each c5b-8 complex.