Osteopontin, Histag, Mouse, Recombinant Protein, Mouse, Each

Details:

Recombinant, mouse osteopontin fused at the c-terminus to a his·tag™ sequence and expressed in nso-derived leu17-asn294 (glu99gly) murine myeloma cells. A secreted, highly acidic, ca2 -binding, rgd-containing, phosphorylated glycoprotein. Chemotactic for macrophages, smooth muscle cells, endothelial cells, and glial cells. Has been shown to inhibit nitric oxide production and cytotoxicity by activated macrophages. Plays a significant role in inducing granulomas of various origin. Opn is also involved in the migration of embryonic fibroblasts, macrophages, and metastatic cells.