Ephb4, Rabbit, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Ephb4, Each

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Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-a (efna) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-b (efnb) class, which are transmembrane proteins. The eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-a and ephrin-b ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (rtk) family. The protein encoded by this gene binds to ephrin-b2 and plays an essential role in vascular development. [Provided by refseq