Fbxo5, Rabbit, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Fbxo5, Each

Details:

This gene encodes a member of the f-box protein family which is characterized by an approximately 40 amino acid motif, the f-box. The f-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called scfs (skp1-cullin-f-box), which function in phosphorylation-dependent ubiquitination. The f-box proteins are divided into 3 classes: fbws containing wd-40 domains, fbls containing leucine-rich repeats, and fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (emi1), which is a mitotic regulator that interacts with cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [Provided by refseq]