Fbxw11, Rabbit, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Fbxw11, Each

Details:

This gene encodes a member of the f-box protein family which is characterized by an approximately 40 amino acid motif, the f-box. The f-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called scfs (skp1-cullin-f-box), which function in phosphorylation-dependent ubiquitination. The f-box proteins are divided into 3 classes: fbws containing wd-40 domains, fbls containing leucine-rich repeats, and fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the fbws class and, in addition to an f-box, contains multiple wd40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [Provided by refseq]