Fgr Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Recombinant Fgr, Each

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This gene is a member of the src family of protein tyrosine kinases (ptks). The encoded protein contains n-terminal sites for myristylation and palmitylation, a ptk domain, and sh2 and sh3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with epstein-barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [Provided by refseqsequence: vfckklepvatakedaglegdfrsygaadhygpdptkarpassfahipnysnfssqainpgfldsgtirgvsgigvtlfialydyearteddltftkgekfhilnntegdwwearslssgktgcipsnyvapvdsiqaeewyfgkig