Hdac4 Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Hdac4, Each

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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to dna. The protein encoded by this gene belongs to class ii of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind dna directly, but through transcription factors mef2c and mef2d. It seems to interact in a multiprotein complex with rbap48 and hdac3. [Provided by refseq