Heparg Cells, Cryopreserved, Heparg Cells, Cryopreserved, Each

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The heparg™ cell line is an immortalized hepatic cell line that retains many characteristics of primary human hepatocytes. Heparg™ cells are terminally differentiated and provided in a convenient cryopreserved format. For scientists who need reproducible metabolism data, heparg™ cells are an in vitro tool that provides reproducible results in a metabolically complete and scalable system.Obtain biologically relevant results from a metabolically complete systemassess the drug-drug interaction potential of your compoundexperience reproducible results from a single population of cellsbiologically relevantheparg™ cells exhibit many characteristics of primary human hepatocytes including morphology, expression of key metabolic enzymes, expression of nuclear receptors, and drug transporters. Unlike hepg2 and fa2n-4 cells, heparg™ cells have high p450 activity and complete expression of all nuclear receptors.Predict metabolism-based drug-drug interactionheparg™ cells respond to prototypical p450 inducers and inhibitors to the same extent as primary hepatocytes, allowing heparg™ cells to be used to evaluate potential drug-drug interactions.Infinitely reproducibleheparg™ cells exhibit many characteristics of primary human hepatocytes and are essentially a single donor. These features allow users to obtain physiological relevant results for metabolism-based drug-drug interactions without the concern of donor variability and limited lot sizes that come with relying on donor tissue. (Note: the cells we provide are terminally differentiated).Heparg™ is a trademark of biopredic international.