Hla-Dr Mouse Anti-Human, Apc-R700, Clone: G46-6, Bd, Mouse Monoclonal Antibody, Each

Details:

The g46-6 monoclonal antibody specifically binds to hla-dr, a major histocompatibility complex (mhc) class ii antigen. Hla-dr antigens are encoded by genes within the human leukocyte antigen (hla) complex located on chromosome 6. Hla-dr is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kda) and a β subunit (27 kda) expressed primarily on antigen presenting cells: b cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. Hla-dr is also expressed on activated t cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to cd4-positive t cells.