Hooke Kits For Eae Induction In C57bl/6 Mice, Each

Details:

Hooke kits™ for eae induction in c57bl/6 mice. Emulsion supplied in pre-filled syringes, ready to use. Consistently induces eae in female c57bl/6 mice eae will develop in 90-100% of mice. Disease onset is 9 to 14 days after immunization. Mean maximum score will be 3.0 To 3.5. Each lot is tested and individually adjusted to ensure consistent disease induction. On day 0, mog35-55/cfa or mog1-125/cfa emulsion and pertussis toxin are injected. On day 1, a second dose of pertussis toxin is injected.Roperly prepared emulsions are critical for reliable induction of many autoimmune disease models. Our emulsions are carefully made and pre-filled into syringes, ready to use, to reduce time needed to set up experiments.Lot-to-lot reagent variations can cause dramatic changes in severity of induced autoimmune disease.