Iars, Rabbit, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Partial Recombinant Iars, Each

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Aminoacyl-trna synthetases catalyze the aminoacylation of trna by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in trnas, aminoacyl-trna synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-trna synthetase belongs to the class-i aminoacyl-trna synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' utrs. [Provided by refseq