Ifn-Γ Mouse Anti-Human, Brilliant Violet 421, Clone: 4s.B3, Bd, Mouse Monoclonal Antibody, Each

Details:

The 4s.B3 monoclonal antibody specifically binds to interferon-γ(ifn-γ). The immunogen used to generate this hybridoma was partially purified human ifn-γobtained from supernatants of human pbmc stimulated with staphylococcus aureus . Interferon-γ(ifn-γ) is a potent multifunctional cytokine that is produced by several activated cell types including nk, nkt, cd4 tcrαβ , cd8 tcrαβ , and tcrγδ t cells. Ifn- γexerts its biological effects through specific binding to the high-affinity ifn-γreceptor complex comprised of ifn-γrα (cd119) and ese influences can involve ifn- γ’s capacity to boost mhc class i and ii expression by antigen-presenting cells as well as to direct effects on b cells and t cells themselves. Human ifn-γis a 14- 18 kda glycoprotein containing 143 amino acid residues.