Il-31 Rabbit Anti-Human, Rabbit Recombinant Polyclonal Antibody, Each

Details:

Interleukin 31, or il-31 is a cytokine secreted by differentiated cd4 t helper type 2 (th2) cells. It is also released during inflammation of the skin, by macrophages and t cells. Because il-31 is secreted by activated th2 cells, it has a role in host defense against infection and may be involved in asthma, allergy and different types of bowel diseases.Abfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. Abfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with protein a. Abfinity™ oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.Intact igg appears on a non-reducing gel as ∽150kda band and upon reduction generating a ∽25kda light chain band and a ∽50kda heavy chain.