Il-8 (Cxcl8) Rabbit Anti-Human, Rabbit Recombinant Polyclonal Antibody, Each

Details:

This antibody is predicted to react with non-human primate and rabbit based on sequence homology. Intact igg appears on a non-reducing gel as ∽150 kda band and upon reduction generating a ∽25 kda light chain band and a ∽50 kda heavy chain. Recombit rabbit polyclonal antibodies are unique offerings from thermo fisher scientific. They are comprised of a selection of multiple different recombit monoclonal antibodies, providing the best of both worlds – the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombit antibody. While functionally the same as a polyclonal antibody – recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets – a recombit rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.Interleukin 8 is a pro-inflammatory factor which belongs to the cxc subfamily of chemokinesk, and which are bound by the cell surface receptors il-8ra and il-8rb. Il-8 functions as a chemoattractant and is a potent angiogenic factor. The expression and secretion of il-8 can be induced by diverse inflammatory stimuli in many cells, including macrophages and endothelial cells. In endothelial cells, il-8 is present in storage vesicles called weibel-palade bodies.