Il10, Sheep, Polyclonal Antibody, Abnova, Sheep Polyclonal Antibody Raised Against Partial Length Recombinant Il10, Each

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The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of th1 cytokines, mhc class ii ags, and costimulatory molecules on macrophages. It also enhances b cell survival, proliferation, and antibody production. This cytokine can block nf-kappa b activity, and is involved in the regulation of the jak-stat signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [Provided by refseq