Il4 Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Il4, Each

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The protein encoded by this gene is a pleiotropic cytokine produced by activated t cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to il13, which may contribute to many overlapping functions of this cytokine and il13. Stat6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, il3, il5, il13, and csf2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to il13. This gene, il13 and il5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [Provided by refseq