Il7, Rabbit, Biotin, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Full-Length Recombinant Il7, Each

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The protein encoded by this gene is a cytokine important for b and t cell development. This cytokine and the hepatocyte growth factor (hgf) form a heterodimer that functions as a pre-pro-b cell growth-stimulating factor. This cytokine is found to be a cofactor for v(d)j rearrangement of the t cell receptor beta (tcrb) during early t cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [Provided by refseq