Map4k4 Rabbit Anti-Human, Mouse, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Map4k4, Each

Details:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate mapk8/jnk. The activation of mapk8 by this kinase is found to be inhibited by the dominant-negative mutants of map3k7/tak1, map2k4/mkk4, and map2k7/mkk7, which suggests that this kinase may function through the map3k7-map2k4-map2k7 kinase cascade, and mediate the tnf-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [Provided by refseq