Mdc1 Rabbit Anti-Human, Polyclonal Antibody, Abnova, Rabbit Polyclonal Antibody Raised Against Synthetic Peptide Of Mdc1, Each

Details:

The protein encoded by this gene contains an n-terminal forkhead domain, two brca1 c-terminal (brct) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-s phase and g2/m phase cell cycle checkpoints in response to dna damage. This nuclear protein interacts with phosphorylated histone h2ax near sites of dna double-strand breaks through its brct motifs, and facilitates recruitment of the atm kinase and meiotic recombination 11 protein complex to dna damage foci. [Provided by refseq