Mrs 1220, Highly Potent And Selective Ha3 Antagonist, Each

Details:

A potent and highly selective antagonist at the human a3 adenosine receptor (ki values are 0.65, 305, And 52 nm at ha3, ra1 and ra2a respectively. Displays an ic50 value > 1 μm for inhibition of binding to rat a3 receptors).