Pd Amination Strong And Weak Base, Each

Details:

The pd catalyzed amination kits  are ideal tools for the investigation of cross-coupling reaction conditions. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed catalysts and reagents. The kit contains all reagents and supplies to perform the reaction conditions. We offer pre-selected arrays of precatalysts and salts or custom arrays depending on your needs.Palladium catalyzed amination  (buchwald-hartwig amination) can be performed using a wide variety of palladium sources, ligands, bases and solvents. We designed 2 kits using a combination of palladium precatalysts with either strong bases or weak bases.Benefits:facilitates screen of reaction conditionsno glove-box needed to manipulate air sensitive or moisture sensitive reagentsenables up to 32 reaction conditions simultaneouslysave substrate using low scale reaction conditionssave time on optimizationfeatures:0.3 Ml crimped vial with stirring bar.Specifically designed reaction blockpre-weighed reagents and catalyststemperature from 0°c to 120°cpre-designed or custom arrays availableavailable kits: palladium weak base kits -  high temperature reaction, compatibility with functional group palladium strong base kits - low temperature reaction, low catalyst loadingkey variables:pd source: pd(oac)2,pd(dppf)2cl2, pd-precatalysts…ligand: phosphine derivatives, brettphos, ruphos, xphos…base: na2co3, cs2co3, k3po4, lhmds, naotbu…solvent: dioxane, nbuoh, tbuoh, toluene, dmf, ch3cn…temperature: rt -> 120c